The carbothermic reaction is analogous to the Kroll process for the conversion of titanium dioxide to titanium tetrachloride. In the laboratory BF3 reacted with AlCl3 gives BCl3 via halogen exchange. BCl3 is a trigonal planar molecule like the other boron trihalides, and has a bond length of 175pm.
A degree of π-bonding has been proposed to explain the short B− Cl distance although there is some debate as to its extent. It does not dimerize, although NMR studies of mixtures of boron trihalides shows the presence of mixed halides. The absence of dimerisation contrasts with the tendencies of AlCl3 and GaCl3, which form dimers or polymers with 4 or 6 coordinate metal centres.
B-cell CLL/lymphoma 9 protein is a protein that in humans is encoded by the BCL9gene.
BCL9, together with its paralogue gene BCL9L (BCL9 like or BCL9.2), have been extensively studied for their role as transcriptional beta-catenin cofactors, fundamental for the transcription of Wnt target genes.
BCL9 and BCL9L have been shown to take part in other tissue-specific molecular mechanisms, showing that their role in the Wnt signaling cascade is only one aspect of their mode of action.
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies.
BCL9 and BCL9L are potential clinical targets for human cancers; for instance, the gene expression changes that they promote is associated with a poor outcome in colorectal cancer.
B-cell lymphoma 3-encoded protein is a protein that in humans is encoded by the BCL3gene.
This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional coactivator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B.
Following the appointment of yet another Canadian outfit, Premium Nickel Resources (PNR) as the preferred bidder in the revival of BCLMines, Moagi revealed they are expecting feedback from the company by the end of August.
Behind a star-studded display led by junior Jashua Delacruz’ three event wins, the Jets handily staved off a talented Charlestown team for nearly a 100-point difference in their third BCL title win over the last four seasons ... On the girls’ side, a deep tradition of winning the BCL ...
For most of the BostonCityLeague championship on Sunday at BC High, LatinAcademy led Snowden, and the Dragons were in position to win. But with three runs in the seventh, Snowden extended play, and then added another in the eighth to rally for a 5-4 victory and third straight BCL title ... “We couldn’t lose. We couldn’t.” ... ....
The company has built a pipeline of eight clinical drug candidates, including novel, highly potent Bcl-2, and dual Bcl-2/Bcl-xL inhibitors, as well as candidates aimed at IAP and MDM2-p53 pathways, and next-generation tyrosine kinase inhibitors (TKIs).
The LatinAcademy girls volleyball team ended its title drought on Friday, dethroning O’Bryant in the BCL Championship with a 3-1 win in the battle of league unbeatens, finishing a competitive 25-19, 15-25, 25-22, 25-10 match with authority to close out Fall II at 12-1 overall.
The economic slump in the SPEDU region following the closure of BCLMine in 2016, was recently made clear with official statistics showing that just 2,294 jobs out of a targetted 6,856 were created in the area since April 2017... At the time of its closure, BCL Mine directly employed 4,287 workers, with 2,959 of these underground in the four shafts.